Letrozole vs estradiol valerate induced PCOS in rats: glycemic, oxidative and inflammatory status assessment
نویسندگان
چکیده
منابع مشابه
Stereological study of the effects of letrozole and estradiol valerate treatment on the ovary of rats
OBJECTIVE Letrozole and estradiol valerate are used to treat some hormonally-responsive symptoms and also in modeling of the polycystic ovary syndrome. However, the stereological analysis of the ovary has received less attention. Estimation of the whole ovary volume using the Cavalieri method can be applied in any orientation desired, but estimation of the mean volume of the oocytes requires is...
متن کاملChanges of The Uterine Tissue in Rats With Polycystic Ovary Syndrome Induced by Estradiol Valerate
Objective : Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. Reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. In this study, the effect of PCOS induction was studied using estradiol valerate. MaterialsAndMethods Adult ...
متن کاملP-185: Hawthorn Berries Ethanolic Extract Lowered Polycystic Ovarian Syndrome- Elevated RNA Damage in Follicular Cells
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder. Various constituents including flavonoids with biological activities including free radical scavenging, anti-lipoperoxidation and anti-inflammatory have been isolated from hawthorn. Due to adverse effect of PCOS on ovarian vascular remodeling as well as PCOS-induced oxidative stress, we aimed to study the hawthorn’s berri...
متن کاملEffect of exercise intensity on weight changes and sexual hormones (androstenedione and free testosterone) in female rats with estradiol valerate-induced PCOS
INTRODUCTION Weight gain and fat accumulation are predisposing factors of PCOS. Life-style modification, including increasing physical activity, is the first line approach in managing PCOS. The objective of this study is to assess the effect of exercise intensity on weight changes, androstenedione and free testosterone level in female rats with estradiol valerate induced PCOS. METHOD AND MATE...
متن کاملبررسی عصاره آبی الکلی گیاه کاکوتی (Ziziphora tenuior L.) بر سندرم تخمدان پلی‌کیستیک در رت ویستار
Background: Polycystic ovary syndrome (PCOS) that occurs with chronic lack of ovulation, systemic inflammation and hyperandrogenism is manifested most common endocrine disorder in women of reproductive age. Ziziphora tenuior L. due to possess its Pulegone, flavenoid and anthocyanin has anti-inflammatory and anti-oxidant activity. This study investigates the modulating effects of Ziziphora tenui...
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ژورنال
عنوان ژورنال: REPRODUCTION
سال: 2016
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-15-0352